Timothy Shannon, M.D.
Dr. Shannon is the Chairman of the Board of Arvinas and a Venture Partner at Canaan Partners. He also serves on the boards of Canaan portfolio companies IDEAYA Biosciences, Nextcure, Spyryx Biosciences, Vivace Therapeutics, and VaxInnate Corporation.
Previously, Dr. Shannon was President and Chief Executive Officer of CuraGen, a biopharmaceutical company focused on oncology, after serving as Executive Vice President of R&D and Chief Medical Officer. He also held positions of increasing responsibility for Bayer’s Pharmaceutical Business Group, including Senior Vice President of Global Medical Development. Prior to his career in industry, Dr. Shannon was an Assistant Professor in the Pulmonary and Critical Care Division at Yale University School of Medicine.
Dr. Shannon received his postgraduate medical training at the Beth Israel Hospital of Harvard Medical School and Boston University. He earned his medical degree from the University of Connecticut and has a B.A. in Chemistry from Amherst College.
Ted Kennedy, Jr.
Ted is a Partner and Member of the Health Care and Life Sciences practice of Epstein Becker Green, a national law firm. A regulatory attorney for over 20 years, Ted counsels health care companies on the legal, reimbursement, coding and coverage issues facing providers, payers and the life sciences industry. Ted has also been an active leader in health care policy and in the movement to expand equal rights and opportunities to people with disabilities, and serves as Board Chair of the American Association of People with Disabilities. Ted received a J.D. from the University of Connecticut School of Law, an M.E.S. from the Yale School of Forestry and Environmental Studies, and a B.A. from Wesleyan University. In 2014, Ted was elected State Senator in the Connecticut General Assembly.
John G. Houston, Ph.D.
Dr. Houston is President and Chief Executive Officer of Arvinas. Previously, he was the SVP of Specialty Discovery at Bristol-Myers Squibb (BMS). He spent more than 18 years at BMS in roles of increasing responsibility and had accountability for all Discovery Biology disease teams as well as various Discovery technology departments. He was also the site head of the BMS Connecticut facility. Dr. Houston was a member of the BMS R&D Executive Leadership team and chaired the Target Portfolio Committee which had governance oversight in the discovery space. With his teams and research colleagues, he progressed over 200 compounds into early development, several of which advanced into late stage clinical trials, and toward commercialization.
He was also the principal architect and driver of the ‘Leveraging Technology’ initiative at BMS which oversaw the design and implementation of an industry-leading integrated lead discovery and optimization process. This initiative created revolutionary changes in the discovery process at BMS with significant improvements in capacity, speed and cost control resulting in marked increases in research productivity and success rates.
Dr. Houston has over 28 years of experience in the pharmaceutical industry. Prior to joining Bristol-Myers Squibb, he worked at Glaxo Welcome Research and Development in the UK, where he served as head of the Lead Discovery Unit.
Dr. Houston obtained his B.Sc degree in Medical Microbiology from Glasgow University and obtained his Ph.D. with Professor Brian Catley in Microbial Biochemistry from Heriot-Watt University, Edinburgh. He also completed his post-doctoral studies on an MRC grant with Professor Julia Douglas at Glasgow University.
Jakob Loven, Ph.D.
Dr. Loven is Partner at Nextech Invest Ltd., a leading, global oncology investment firm that focuses on early, private-stage cancer companies. A scientific entrepreneur and biotech venture capitalist, Dr. Loven has extensive experience in creating, launching, and building early stage therapeutic companies in the US and most recently led the $57M launch of Relay Therapeutics from Third Rock Ventures, joining the company full time to lead corporate strategy, business development, and operations. Prior to Relay, Dr. Loven was a Scientific Co-Founder of Syros Pharmaceuticals (NASDAQ: SYRS) and was involved from its inception in April 2013 to advancing the pipeline to its first clinical candidate and growing the company to 30+ employees, culminating in its initial public offering in July 2016. Jakob holds a BA in Biomedical Sciences from the Anglia Ruskin University of Cambridge, earned his Ph.D. in Medical Sciences from Karolinska Institutet, and conducted his postdoctoral fellowship at the Whitehead Institute for Biomedical Research.
Mr. Margus currently serves as Co-Founder and Chief Executive Officer of Cerevance, a drug discovery company focused on brain diseases with sites in Massachusetts and the United Kingdom. From 2009-2012, as Chief Executive Officer of Envoy Therapeutics, he raised $8 million from investors, employed a unique technology to discover new compounds for brain diseases, and sold the company within three years for $140 million. From 2000 to 2007, Mr. Margus was the Chief Executive Officer of Perlegen Sciences, a leader in analyzing genetic variation that raised $257 million from investors, exceeded $100 million in revenues, and identified diagnostic markers for disease risk and drug response.
Mr. Margus has been a member of numerous government advisory committees as well as corporate and nonprofit boards. He currently serves on the Boards of Second Genome, Presage Biosciences and the non-profit A-T Children’s Project. Additionally, he serves as the Chair of the Network for Excellence in Neuroscience Clinical Trials External Oversight Board at the NIH.
Mr. Margus obtained his M.B.A. from Harvard Business School.
Briggs Morrison, M.D.
Dr. Morrison received his B.S. in biology from Georgetown University, his M.D. from the University of Connecticut Medical School, completed residency training in Internal Medicine at the Massachusetts General Hospital, and completed a fellowship in Medical Oncology at Dana-Farber Cancer Institute. He did postdocs with Philip Leder at Harvard Medical School, and Lee Nadler at the Dana-Farber. He joined Merck & Co., Inc. in 1995, was appointed Head of Clinical Development at Pfizer in 2007, and became Head of Global Medicines Development and Chief Medical Officer at AstraZeneca in 2012. He is currently the CEO of Syndax Pharmaceuticals.
Dr. Morrison has overseen the development of numerous biopharmaceutical products in multiple therapeutic areas, from first-in-human trials through to global regulatory approvals. He is currently a board member of private companies Oncorus and Repare Therapeutics, and is an advisor to a number of other private biotechnology companies. In addition, Dr. Morrison is a board member of the Alliance for Clinical Research Excellence and Safety (ACRES), a non-profit organization dedicated to optimizing the global clinical research system.
Kush M. Parmar, M.D., Ph.D.
Dr. Parmar is a Partner at 5AM Ventures. He currently serves as Director or Observer on the Boards of Achaogen, Arvinas, Audentes Therapeutics, Cleave Biosciences, Novira Therapeutics and Pulmatrix, and previously served as Board Observer for Envoy (acquired by Takeda). Dr. Parmar is a Fellow of the Society of Kauffman Fellows.
Previously, he was an NIH-sponsored M.D./Ph.D. Physician Scientist Fellow at Harvard Medical School, where he completed clinical clerkships at the Massachusetts General Brigham and Women’s Hospitals. Dr. Parmar also founded a nonprofit international development organization called the Cruz Blanca Initiative.
Dr. Parmar received an A.B. in Molecular Biology and Medieval Studies from Princeton University, a Ph.D. in Experimental Pathology from Harvard University and an M.D. from Harvard Medical School.
Liam Ratcliffe, M.D., Ph.D.
Dr. Ratcliffe is a Managing Director at New Leaf Venture Partners, where he concentrates on biopharmaceutical investing. He joined New Leaf in September 2008. Dr. Ratcliffe previously served as Senior Vice President and Development Head for Pfizer Neuroscience, as well as Worldwide Head of Clinical Research and Development. Additional positions during his 12 years at Pfizer included Vice President of Exploratory Development for the Midwest region (based in Ann Arbor, Mich.) and Head of Experimental Medicine at Pfizer’s Sandwich, UK Laboratories.
Dr. Ratcliffe received his M.D. and Ph.D. in Immunology from the University of Cape Town and his M.B.A. from the University of Michigan. He completed his internal medicine training and fellowship in Immunology at Groote Schuur Hospital and associated teaching hospitals in Cape Town, South Africa.