Careers

Careers at Arvinas

Open Positions

Arvinas, Inc. is seeking qualified candidates for the following open positions:

Biology

Research Investigator/ Scientist, Neurophysiology

Arvinas is a pharmaceutical company focused on developing new small molecules ‒ known as PROTACs (PROteolysis TArgeting Chimeras) ‒ aimed at degrading disease-causing cellular proteins via proteolysis. Based on innovative research conducted at Yale University by Dr. Craig Crews, Founder and Chief Scientific Advisor, the company is translating natural protein degradation approaches into novel drugs for the treatment of cancer and other diseases. The proprietary PROTAC-based drug paradigm induces protein degradation, rather than protein inhibition, using the ubiquitin proteasome system and offers the advantage of potentially targeting “undruggable” as well as “druggable” elements of the proteome. This greatly expands the ability to create drugs for many new, previously unapproachable targets. For more information, visit www.arvinas.com.

Position Summary

We are seeking a highly motivated senior scientist to join our efforts in the Neuroscience and Platform Biology Team to contribute to building our discovery pipeline for neurodegenerative diseases.  This individual will contribute and lead scientific efforts focused on building a relationship between gene expression correction and functional physiologic improvement of disease phenotypes in complex human rodent neuronal models.

Principal Responsibilities

  • Expert in all aspects of neuronal cell biology with a deep understanding of synaptic physiology and higher throughput approaches to assess neuronal cell function.
  • Deep knowledge of molecular, biochemical and pharmacologic techniques required to examine target expression, modulation and function.
  • Demonstrated ability to perform in vitro electrophysiological recordings in ex-vivo preparations from brain or spinal cord. Specifically, experience in the cell culture techniques; electrical recording and data analysis utilizing multi-electrode arrays is required.
  • Experience in whole cell patch clamp techniques in either clonal or primary cultured cells (including neurons) is desired.
  • Proficiency in development of optical and image-based assay approaches and software for analysis of electrophysiologic experiments is desired (i.e., MATLAB). Ability to identify and solve technical issues that arise with electrophysiology equipment, especially high throughput electrophysiological recording equipment is required.
  • Experience and effectiveness working in a multidisciplinary team drug discovery environment with common goals and operating in a matrixed environment is essential.
  • Excellent written and oral communication as demonstrated in the quality of interactions on projects in a team environment, written reports and publications focused on network electrophysiology especially slice and MEA techniques.
  • Skilled in pharmacologic assessment of both small molecules and other therapeutic modalities in primary or stem cell derived cellular systems.
  • Knowledge, application and analysis of compound pharmacology testing using in vitro disease models.
  • Able to lead drug discovery programs and collaboratively to contribute to drug discovery.

Qualifications

  • Ph.D. in biochemistry, pharmacology, or neuroscience with at least 5+ years of relevant post-doctoral and / or industry experience in neurologic and/ or muscle and/ or cardiovascular monogenic diseases that includes a robust publication record and experience with in vitro physiology of disease models.
  • Strong oral and written communication skills and a desire to work in a team environment are essential.
  • Manages time and balances work between bench and desk

Please send CV and cover letter to: careers@arvinas.com

Arvinas is proud to offer a competitive package of base and incentive compensation as well as a comprehensive benefits program designed to support the health, wellness and financial security of our employees and their families. Benefits include group medical, vision and dental coverage, group and supplemental life insurance, and much more. To learn more about Arvinas, please visit www.arvinas.com

Arvinas is an Equal Opportunity employer   

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Research Investigator/ Scientist, Neurodegeneration

Arvinas is a pharmaceutical company focused on developing new small molecules ‒ known as PROTACs (PROteolysis TArgeting Chimeras) ‒ aimed at degrading disease-causing cellular proteins via proteolysis. Based on innovative research conducted at Yale University by Dr. Craig Crews, Founder and Chief Scientific Advisor, the company is translating natural protein degradation approaches into novel drugs for the treatment of cancer and other diseases. The proprietary PROTAC-based drug paradigm induces protein degradation, rather than protein inhibition, using the ubiquitin proteasome system and offers the advantage of potentially targeting “undruggable” as well as “druggable” elements of the proteome. This greatly expands the ability to create drugs for many new, previously unapproachable targets. For more information, visit www.arvinas.com.

Position Summary

As one of the key hires for the company, you will work in close collaboration with leaders and scientists to ensure progression of PROTACs in neurologic disorders.  This highly motivated individual with expertise in molecular, biochemical, histologic and mechanistic basis of neurodegeneration will apply PROTACs to degrade target proteins in support of the cancer and neurology discovery portfolio.  As a drug hunter, you will be responsible for contributing to critical path lead optimization efforts, development candidate identification and contributions to IND filings.

Principal Responsibilities

  • Build and conduct assays as part of a decisional screening tier aimed at informing PROTAC induced degradation of pathologic protein aggregates in neurodegenerative diseases.
  • Molecular-genetic, circuitry level understanding of neurodegeneration; and examples of incorporating this knowledge into drug discovery.
  • Experience in developing assays to profile compounds using target engagement, mechanistic and functional readouts in neuronal and/ or in vivo models.
  • Experience in the characterization biochemical oligomeric neurodegenerative protein species, effects on neuronal dysfunction and pathologic seeding and extracellular neuronal propagation, is preferred.
  • Demonstrated success in working on a cross-disciplinary, drug discovery project team; integrating and evaluating the work of multiple drug discovery groups / functions.
  • Expertise in developing compound profiling assays to support chemistry efforts in developing structure-activity relationships that guide lead identification, optimization & development candidate selection.
  • Ability to build exposure and pharmacodynamic relationships in preclinical models to drive a human dose projection. Knowledge of assays & metrics that report on potency, selectivity, ADME, PK, PD & efficacy.
  • Solid understanding of how to leverage CSF, imaging and functional biomarkers to contribute to translational research plans for clinical studies.
  • Excellent communication, including oral presentation and written, skills that can easily be applied to data summaries for regulatory agencies.

Qualifications

  • Ph.D., with 5+ years of post-doctoral experience in cellular and molecular biology, neurobiology, pharmacology or enzymology. Focus on neurobiology and drug discovery preferred with strong publication record.
  • Innovative, creative, inquisitive, motivated researcher with strong problem-solving skills and demonstrated ability to advance new scientific understanding
  • Experience in the ubiquitin-proteasome system, or targeted protein degradation, a plus
  • Manages time and balances work between bench and desk

Please send CV and cover letter to: careers@arvinas.com

Arvinas is proud to offer a competitive package of base and incentive compensation as well as a comprehensive benefits program designed to support the health, wellness and financial security of our employees and their families. Benefits include group medical, vision and dental coverage, group and supplemental life insurance, and much more. To learn more about Arvinas, please visit www.arvinas.com

Arvinas is an Equal Opportunity employer   

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Senior Research Scientist/Research Investigator, Biology

Arvinas is a pharmaceutical company focused on developing new small molecules ‒ known as PROTACs (PROteolysis TArgeting Chimeras) ‒ aimed at degrading disease-causing cellular proteins via proteolysis. Based on innovative research conducted at Yale University by Dr. Craig Crews, Founder and Chief Scientific Advisor, the company is translating natural protein degradation approaches into novel drugs for the treatment of cancer and other diseases. The proprietary PROTAC-based drug paradigm induces protein degradation, rather than protein inhibition, using the ubiquitin proteasome system and offers the advantage of potentially targeting “undruggable” as well as “druggable” elements of the proteome. This greatly expands the ability to create drugs for many new, previously unapproachable targets. For more information, visit www.arvinas.com.

Qualifications

  • Innovative, creative, inquisitive, motivated researcher with strong problem-solving skills and demonstrated ability to advance new scientific understanding
  • Strong expertise in cancer cell biology, drug discovery approaches and biochemical and biophysical techniques
  • Strength in running and evaluating experiments to measure target engagement, protein degradation, pathway modulation and therapeutic sensitivity in response to compounds
  • Experience in developing assays to profile compounds using mechanistic and functional readouts
  • Demonstrated success in working on a cross-disciplinary, drug discovery project team; integrating and evaluating the work of multiple drug discovery groups / functions
  • Excellent communication and interpersonal skills

Education

  • Ph.D, with 3+ years of pharma- or biotech experience in cellular and molecular biology, pharmacology, biochemistry, biophysics or enzymology
  • Focus on cancer biology, target validation, and drug discovery strongly preferred
  • Experience in immuno-oncology recommended, but not required

Other Preferred Skills and Knowledge

  • Manages times and balances work between bench and desk
  • Maintains accountability for ensuring own goals, those of any direct reports and company objectives are achieved
  • Maintains a safe working environment for self and others
  • Represents the company effectively to external organizations and to the Board of Directors and other company senior management, as needed/requested
  • Writes procedures/protocols and professional/technical reports and writes scientific articles, publications and patents

 

Please send CV and cover letter to: careers@arvinas.com

 

Arvinas is proud to offer a competitive package of base and incentive compensation as well as a comprehensive benefits program designed to support the health, wellness and financial security of our employees and their families. Benefits include group medical, vision and dental coverage, group and supplemental life insurance, and much more. To learn more about Arvinas, please visit www.arvinas.com

Arvinas is an Equal Opportunity employer   

Continue reading →

Research Investigator/Sr. Research Investigator, Platform Biology

Arvinas is a pharmaceutical company focused on developing new small molecules ‒ known as PROTACs (PROteolysis TArgeting Chimeras) ‒ aimed at degrading disease-causing cellular proteins via proteolysis. Based on innovative research conducted at Yale University by Dr. Craig Crews, Founder and Chief Scientific Advisor, the company is translating natural protein degradation approaches into novel drugs for the treatment of cancer and other diseases. The proprietary PROTAC-based drug paradigm induces protein degradation, rather than protein inhibition, using the ubiquitin proteasome system and offers the advantage of potentially targeting “undruggable” as well as “druggable” elements of the proteome. This greatly expands the ability to create drugs for many new, previously unapproachable targets. For more information, visit www.arvinas.com.

Position Summary

Your focus will be to build innovative in vitro assay approaches to investigate mechanisms of protein degradation.  As one of the key hires for the company, you will work in close collaboration with leaders and scientists to ensure that our platform technology evolves based on a rigorous scientific foundation.  Our aim is to further understand the underlying principles of PROTACs and continue to evolve our protein degradation platform in areas of high unmet medical need including cancer and neurodegeneration.

Principal Responsibilities

  • Application of strong expertise in molecular biology, cell biology, drug discovery approaches and biochemical and biophysical techniques to study PROTAC engagement of the ubiquitin proteasome system, or targeted protein degradation
  • Strength in executing and evaluating experiments to measure target engagement, protein degradation, pathway modulation and therapeutic sensitivity in response to compounds to develop structure-activity relationships
  • Experience in developing assays to profile compounds using mechanistic and functional readouts (intracellular binding approaches, bioluminescence (nanoBRET), fluorescence (FRET), High Content Imaging- a plus)
  • Strong expertise in molecular biology using siRNA/ ASOs, CRISPR knock out and mutagenesis strategies, and generation of relevant cell models to study targeted degradation in disease context.
  • Demonstrated success in working on a cross-disciplinary, drug discovery project team; integrating and evaluating the work of multiple drug discovery groups / functions
  • Expertise in developing compound profiling assays to support chemistry efforts in developing structure-activity relationships
  • Excellent communication and interpersonal skills
  • Supervisory experience

Qualifications

  • PhD, with 5+ years of pharma/ biotech/ academic experience in cellular and molecular biology, pharmacology, biochemistry, biophysics or enzymology. Focus on cancer cell biology and drug discovery strongly preferred.
  • Innovative, creative, inquisitive, motivated researcher with strong problem-solving skills and demonstrated ability to advance new scientific understanding
  • Experience in the ubiquitin-proteasome system, or targeted protein degradation, preferred
  • Manages times and balances work between bench and desk
  • Maintains accountability for ensuring own goals, those of any direct reports and company objectives are achieved
  • Proficient Data with data analysis tools (PRISM, Spotfire/Vortex, Matlab, etc. a plus)
  • Maintains a safe working environment for self and others
  • Represents the company effectively to external organizations and to the Board of Directors and other company senior management, as needed/requested
  • Writes procedures/protocols and professional/technical reports and writes scientific articles, publications and patents

Education

  • Ph.D.

 

Please send CV and cover letter to: careers@arvinas.com

 

Arvinas is proud to offer a competitive package of base and incentive compensation as well as a comprehensive benefits program designed to support the health, wellness and financial security of our employees and their families. Benefits include group medical, vision and dental coverage, group and supplemental life insurance, and much more. To learn more about Arvinas, please visit www.arvinas.com

Arvinas is an Equal Opportunity employer   

Continue reading →

Senior Research Scientist, Platform Biology

Arvinas is a pharmaceutical company focused on developing new small molecules ‒ known as PROTACs (PROteolysis TArgeting Chimeras) ‒ aimed at degrading disease-causing cellular proteins via proteolysis. Based on innovative research conducted at Yale University by Dr. Craig Crews, Founder and Chief Scientific Advisor, the company is translating natural protein degradation approaches into novel drugs for the treatment of cancer and other diseases. The proprietary PROTAC-based drug paradigm induces protein degradation, rather than protein inhibition, using the ubiquitin proteasome system and offers the advantage of potentially targeting “undruggable” as well as “druggable” elements of the proteome. This greatly expands the ability to create drugs for many new, previously unapproachable targets. For more information, visit www.arvinas.com.

 

Position Summary

Your focus will be to develop, implement and execute innovative in vitro assay approaches to investigate mechanisms of protein degradation.  As one of the key hires for the company, you will work in close collaboration with leaders and scientists to ensure that our platform technology evolves based on a rigorous scientific foundation.  Our aim is to further understand the underlying principles of PROTACs and continue to evolve our protein degradation platform in areas of high unmet medical need including cancer and neurodegeneration.

 

Principal Responsibilities

  • Conducting key experiments aimed at elucidating mechanistic PROTAC engagement with components of the ubiquitin-proteasome system in cells
  • Strength in pharmacologic assessment of compounds in endogenous cell systems by assessing targeted degradation and pathway responses.
  • Experience in developing assays to profiling compounds for structure activity relationships using mechanistic, functional medium to high throughput readouts (High Content Image Analysis Quantification and Data reporting, ELISA, quantitative Western, High Content Imaging, Bioluminescent (nanoBRET) / Fluorescence assays, etc.)
  • Molecular techniques including cloning, qPCR, RT-PCR, cell line engineering using CRISPR/Cas9, is a plus
  • Recombinant cell line construction, Lentiviral infection of primary, cancer cell lines and iPSC a plus
  • Experience in utilizing compound inhibitors and molecular target manipulation (e.g. RNAi, CRISPR) to dissect target function and dependency

Qualifications

  • B.S./ M.S. with 12+ years or Ph.D. with 5+ years of pharma- or biotech experience in cellular and molecular biology, pharmacology, biochemistry, biophysics or enzymology. Focus on cancer cell biology and drug discovery strongly preferred.
  • Experience studying the ubiquitin-proteasome system, or targeted protein degradation, preferred
  • Strong expertise in cell biology, drug discovery approaches, biochemical and biophysical techniques
  • Innovative, creative, inquisitive, motivated researcher with strong problem-solving skills and demonstrated ability to advance new scientific understanding.
  • Generate and maintaining clear experimental records.
  • Experience analyzing data using Microsoft Excel, Prism, Spotfire or Vortex or similar multiparametric analytical tool.
  • Excellent communication and interpersonal skills
  • Ability to mentor others
  • Demonstrated success in working on a cross-disciplinary, drug discovery project team; integrating and evaluating the work of multiple drug discovery groups / functions
  • Maintains accountability for ensuring own goals, those of any direct reports and company objectives are achieved
  • Maintains a safe working environment for self and others
  • Contributes data/procedures/protocols for professional/technical reports as well as for scientific publications, patents and regulatory documents

Education

  • Ph.D. or B.S./M.S.

 

Please send CV and cover letter to: careers@arvinas.com

 

Arvinas is proud to offer a competitive package of base and incentive compensation as well as a comprehensive benefits program designed to support the health, wellness and financial security of our employees and their families. Benefits include group medical, vision and dental coverage, group and supplemental life insurance, and much more. To learn more about Arvinas, please visit www.arvinas.com

Arvinas is an Equal Opportunity employer   

Continue reading →

Senior Research Associate/Associate Scientist (Biology)

Arvinas is a pharmaceutical company focused on developing new small molecules ‒ known as PROTACTM protein degraders (PROteolysis TArgeting Chimeras) ‒ aimed at degrading disease-causing cellular proteins via proteolysis. Based on innovative research conducted at Yale University by Dr. Craig Crews, Founder and Chief Scientific Advisor, the company is translating natural protein degradation approaches into novel drugs for the treatment of cancer and other diseases. The proprietary PROTAC-based drug paradigm induces protein degradation, rather than protein inhibition, using the ubiquitin proteasome system and offers the advantage of potentially targeting “undruggable” as well as “druggable” elements of the proteome. This greatly expands the ability to create drugs for many new, previously unapproachable targets.

Education and Training

  • BS/MS with 4+ years of Pharma/Biotech drug discovery experience, or PhD with 2+ years of relevant experience

 

Required Skills and Abilities

  • Experience with biochemical and biophysical assay development, to evaluate compound SAR and characterize mode of action
  • Experience with fluorescence-based assay techniques (e.g. TR-FRET, AlphaLISA, FP, etc.) and label-free technologies (e.g. SPR, MST, etc.) is highly desired
  • A solid understanding of protein biochemistry and enzymology
  • Experience with protein expression and purification is preferred
  • High-throughput assay development and screening, plus experience with automated liquid handling instrumentation experience is also preferred
  • Strength in experimental design, execution, and data analysis
  • Innovative, independent, motivated and productive problem solver with excellent communication skills who also works effectively in a team setting
  • Organized, goal-oriented and timeline-conscious

 

Location

New Haven, CT

Please send CV and cover letter to: careers@arvinas.com

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Associate Scientist / Sr. Associate Scientist (Biology) (4)

Arvinas is a pharmaceutical company focused on developing new small molecules ‒ known as PROTACTM protein degraders (PROteolysis TArgeting Chimeras) ‒ aimed at degrading disease-causing cellular proteins via proteolysis. Based on innovative research conducted at Yale University by Dr. Craig Crews, Founder and Chief Scientific Advisor, the company is translating natural protein degradation approaches into novel drugs for the treatment of cancer and other diseases. The proprietary PROTAC-based drug paradigm induces protein degradation, rather than protein inhibition, using the ubiquitin proteasome system and offers the advantage of potentially targeting “undruggable” as well as “druggable” elements of the proteome. This greatly expands the ability to create drugs for many new, previously unapproachable targets. 

Education and Training

  • BS/MS with 8+ years of Pharma/Biotech drug discovery experience

Preferred Skills and Abilities

  • Innovative, independent, motivated and productive problem solver with excellent communication skills who also works effectively in a team setting
  • Strength in experimental design, execution, and data analysis
  • Organized, goal-oriented and timeline-conscious
  • Strength in leveraging multiple assay platforms for measuring target engagement, pathway modulation and cell sensitivity in response to compounds or target modulation
  • Experience in design, QC and execution of medium- to high- throughput 96/384 well assay formats, such as ELISA, quantitative Western, cell viability/death
  • Molecular techniques: cloning, PCR, RT-PCR, cell line engineering
  • Protein expression and purification

Experience in utilizing compounds and molecular target manipulation (e.g. RNAi) to dissect target function and dependency

Location

New Haven, CT

Please send CV and cover letter to: careers@arvinas.com.

 

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Director/Senior Director, Project Leader, Biology

Arvinas is a pharmaceutical company focused on developing new small molecules ‒ known as PROTACTM protein degraders (PROteolysis TArgeting Chimeras) ‒ aimed at degrading disease-causing cellular proteins via proteolysis. Based on innovative research conducted at Yale University by Dr. Craig Crews, Founder and Chief Scientific Advisor, the company is translating natural protein degradation approaches into novel drugs for the treatment of cancer and other diseases. The proprietary PROTAC-based drug paradigm induces protein degradation, rather than protein inhibition, using the ubiquitin proteasome system and offers the advantage of potentially targeting “undruggable” as well as “druggable” elements of the proteome. This greatly expands the ability to create drugs for many new, previously unapproachable targets. 

Reports to: Vice President, Biology

 

Education and Training

  • PhD, with 15+ years of pharma or biotech drug discovery experience, preferably in oncology. Track record of leading research projects to IND-track nomination.

Position Summary

Responsible for the effective management of assigned therapeutic projects in line with company criteria and timelines within a matrix team environment, particularly in collaboration with partner Chemistry project lead

Provide transparent, focused updates to manager and company executives as requested and represent company at scientific conferences, regulatory body meetings and other external organizations as needed

May supervise/mentor junior PhD biologists

 

Requirements

  • Demonstrated success in leading a cross-disciplinary, drug discovery project team; integrating and evaluating the work of multiple drug discovery groups / functions
  • Innovative, motivated, researcher with strong problem solving and communication skills
  • Strong background in cancer biology and signaling with demonstrated expertise in incorporating this knowledge into drug discovery
  • Expertise in developing compound profiling mechanistic and functional assays to support chemistry efforts in developing structure-activity relationships that guide lead identification, optimization & development candidate selection, specifically, running and evaluating experiments to measure target engagement, pathway modulation and therapeutic sensitivity in response to compounds or target modulation
  • Knowledge of assays & metrics that report on potency, selectivity, ADME, PK, PD, safety & efficacy
  • Some bench work may be expected
  • Solid understanding of how to leverage biomarkers and translational research to guide clinical development
  • Contribute to regulatory documents, scientific publications, patents
  • Make scientific contributions that have significant impact on the Arvinas platform and overall research direction of the company
  • Maintain orderly and timely record of project plans and results in accordance with company policy and legal requirements
  • Accountability for ensuring own goals, those of any direct reports, project team goals, and project and company objectives are achieved
  • Excellent publication record
  • Maintain a safe working environment for self and others

Location

New Haven, CT

Please send CV and cover letter to: careers@arvinas.com.

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Research Scientist/Sr. Research Scientist (Biology) (1)

Arvinas is a pharmaceutical company focused on developing new small molecules ‒ known as PROTACTM protein degraders (PROteolysis TArgeting Chimeras) ‒ aimed at degrading disease-causing cellular proteins via proteolysis. Based on innovative research conducted at Yale University by Dr. Craig Crews, Founder and Chief Scientific Advisor, the company is translating natural protein degradation approaches into novel drugs for the treatment of cancer and other diseases. The proprietary PROTAC-based drug paradigm induces protein degradation, rather than protein inhibition, using the ubiquitin proteasome system and offers the advantage of potentially targeting “undruggable” as well as “druggable” elements of the proteome. This greatly expands the ability to create drugs for many new, previously unapproachable targets. 

Education and Training

  • Ph.D, with 3+ years of post-doctoral experience in cellular and molecular biology, pharmacology or enzymology. Focus on cancer cell biology and drug discovery preferred but not essential

Requirements

  • Innovative, motivated, researcher with strong problem solving and communication skills
  • Strong expertise in drug discovery approaches and scientific techniques
  • Strength in running and evaluating experiments to measure target engagement, pathway modulation and therapeutic sensitivity in response to compounds or target modulation

Preferred but Non-essential Requirements:

  • A Ph.D. or equivalent in biomedical research and a productive post-doctoral fellowship (at least 3 years) with a strong background in cancer biology and signaling and outstanding publications
  • Molecular-genetic understanding of cancer; facility incorporating this knowledge into drug discovery
  • Experience in developing assays to profile compounds using mechanistic and functional readouts
  • A demonstrated ability to be innovating and to advance new scientific understanding
  • Demonstrated success in working on a cross-disciplinary, drug discovery project team; integrating and evaluating the work of multiple drug discovery groups / functions
  • Expertise in developing compound profiling assays to support chemistry efforts in developing structure-activity relationships that guide lead identification, optimization & development candidate selection
  • Solid understanding of how to leverage biomarkers and translational research to guide development of personal medicine
  • Knowledge of assays & metrics that report on potency, selectivity, ADME, PK, PD & efficacy

Location

New Haven, CT

Please send CV and cover letter to: careers@arvinas.com.

 

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Sr. Associate Scientist/Research Scientist (Neurobiology)

Arvinas is a pharmaceutical company focused on developing new small molecules ‒ known as PROTACTM protein degraders (PROteolysis TArgeting Chimeras) ‒ aimed at degrading disease-causing cellular proteins via proteolysis. Based on innovative research conducted at Yale University by Dr. Craig Crews, Founder and Chief Scientific Advisor, the company is translating natural protein degradation approaches into novel drugs for the treatment of cancer and other diseases. The proprietary PROTAC-based drug paradigm induces protein degradation, rather than protein inhibition, using the ubiquitin proteasome system and offers the advantage of potentially targeting “undruggable” as well as “druggable” elements of the proteome. This greatly expands the ability to create drugs for many new, previously unapproachable targets. 

Arvinas is seeking a talented, innovative, and experienced biologist to investigate how targeted-protein degradation can impact neurodegenerative diseases. Successful candidates should be highly motivated and enjoy working in a team-based environment.

This position is laboratory-based and requires strong experimental skills with a background in cell biology, particularly with primary neuronal cultures, and experience in quantitative assay development, cell-based compound screening, biochemical assays, immunocytochemistry, and high-content imaging.

EDUCATION AND TRAINING:

  • BS/MS degree in neurobiology or related discipline
  • 8+ years Biotech/Pharma experience drug discovery experience in neuroscience

RESPONSIBILITIES INCLUDE:

  • Culture and maintenance of cell lines, primary neurons and iPSC-derived neurons
  • Stable cell line generation
  • Assessment of compound efficacy via immunocytochemical, biochemical and molecular biology techniques, such as immunostaining and immunoblotting
  • Interaction and collaboration with biology and chemistry team members to contribute to structure-activity relationship determination
  • Analysis of experimental data, addressing methodological problems in experimental protocols and results
  • Documentation, compilation, and interpretation of experimental data.
  • Presentation of data in oral and written reports in a clear and concise manner to supervisor and project teams
  • Management of laboratory notebook, databases and/or spreadsheets to compile and present results in a meaningful manner
  • Keeping up-to-date on relevant scientific literature

REQUIRED SKILLS AND ABILITIES:

  • Proficiency in basic lab techniques and principles of cell and molecular biology, biochemistry and neurobiology
  • Proficiency in culturing primary neurons and neuronal cell lines
  • Experience in assay validation, assay development and small molecule testing
  • Basic understanding of neurodegenerative diseases
  • Ability to work and problem-solve independently while under general supervision by the project leader

Location

New Haven, CT

Please send CV and cover letter to: careers@arvinas.com.

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Chemistry

Computational Chemist

Arvinas is a pharmaceutical company focused on developing new small molecules ‒ known as PROTACs (PROteolysis TArgeting Chimeras) ‒ aimed at degrading disease-causing cellular proteins via proteolysis. Based on innovative research conducted at Yale University by Dr. Craig Crews, Founder and Chief Scientific Advisor, the company is translating natural protein degradation approaches into novel drugs for the treatment of cancer and other diseases. The proprietary PROTAC-based drug paradigm induces protein degradation, rather than protein inhibition, using the ubiquitin proteasome system and offers the advantage of potentially targeting “undruggable” as well as “druggable” elements of the proteome. This greatly expands the ability to create drugs for many new, previously unapproachable targets. For more information, visit www.arvinas.com.

Position Summary

An ideal candidate would have a well-trained background in molecular modeling or computational chemistry, having the flexibility to be integrated into the current group as well as work collaboratively with chemists and biologists and having the desire to learn and solve challenging problems. Extensive experience in molecular dynamics simulation, free energy prediction or protein-protein docking is highly sought.  This position reports to the Director of Computational Chemistry and will be located at our headquarters in New Haven, CT.

Primary Responsibilities

Key responsibilities of this role include, but are not limited to:

  • Support and drive the discovery and advancement of PROTACTM targeted protein degraders through computational and molecular modeling input.
  • Work closely with medicinal chemists, biologists and pharmacologists to develop and mature hit identification and lead optimization strategies and to execute from a computational perspective.
  • Develop molecular models and SAR rules in both classical and non-classical scenarios.
  • Perform virtual screening and compound design using structure-based design methods.
  • Participate in selecting, evaluating and implementing software suites.
  • Maintain enterprise cheminformatics database and electronic notebook systems.
  • Demonstrate deep expertise in theoretical and hands-on structure-based and ligand-based drug design.
  • Perform work on multiple classes of drug targets.
  • Apply strong understanding of modeling and computational principles related to protein conformation, protein-ligand interaction and physicochemical properties of compounds.

Qualifications

  • > 4 years of drug discovery experience, industrial experience preferred.
  • Work experience in at least two areas from: virtual screening, docking, de novo design, compound redesign or optimization, molecular dynamics simulation, free energy perturbation, QSAR, DMPK models.
  • Advanced knowledge of Schrödinger’s drug discovery suite.
  • Experience in managing Linux workstations and cloud instances is a plus. Experience in cheminformatics is a plus.
  • Development and coding experience is a plus.
  • Strong track-record of patents and publications.
  • A successful candidate will have an enabling attitude, be a problem solver and have a desire to work in a collaborative manner across all the functional areas.
  • Demonstrate excellent communication skills, including oral presentation and writing capabilities.

Education

  • Ph.D. in a computational chemistry/molecular modeling-related area.

 

Please send CV and cover letter to: careers@arvinas.com

Arvinas is proud to offer a competitive package of base and incentive compensation as well as a comprehensive benefits program designed to support the health, wellness and financial security of our employees and their families. Benefits include group medical, vision and dental coverage, group and supplemental life insurance, and much more. To learn more about Arvinas, please visit www.arvinas.com

Arvinas is an Equal Opportunity employer   

Continue reading →

MEDICINAL CHEMISTRY PROJECT LEADER

Arvinas is a pharmaceutical company focused on developing new small molecules ‒ known as PROTACTM (PROteolysis TArgeting Chimera) protein degrader molecules ‒ aimed at degrading disease-causing cellular proteins via proteolysis. Based on innovative research conducted at Yale University by Dr. Craig Crews, Founder and Chief Scientific Advisor, the company is translating natural protein degradation approaches into novel drugs for the treatment of cancer and other diseases. The proprietary PROTAC-based drug paradigm induces protein degradation, rather than protein inhibition, using the ubiquitin proteasome system and offers the advantage of potentially targeting “undruggable” as well as “druggable” elements of the proteome. This greatly expands the ability to create drugs for many new, previously unapproachable targets. For more information, visit www.arvinas.com.

Primary Responsibilities

  • Responsible for the effective management of assigned therapeutic or platform PROTACTM projects in line with target project profiles and timelines within a team environment
  • Requires the expeditious molecular and synthetic design of PROTACs and libraries in conjunction with state-of-the-art computational chemistry resources to enable program advancement
  • Requires a dynamic interaction with external CRO resources to ensure synthetic and data needs are fulfilled according to agreed timelines and standards
  • Requires solicitation and analysis of necessary experimentation/data to allow identification and prioritization of issues, and crisp-decision making within the project environment to meet company, project and personal goals and timelines
  • Ensures that key program progression compounds and data are being generated and decision-making based on strong scientific judgment is occurring.
  • Responsible for providing considered and focused input across all phases of drug discovery, smoothly collaborates with other functions in drug discovery, and exemplifies leadership, demanding excellence in performance at all levels
  • As required to meet goals, personally executes on synthetic routes to pioneer chemistry and address recalcitrant key project molecules and intermediates
  • Provides transparent and coherent and focused updates to manager and company executives on request and represents company interests at conferences and in scientific matters to external organizations as needed

Functional Knowledge and Skills

  • Extensive knowledge of synthetic and medicinal chemistry-related scientific and technological principles to design and execute drug-discovery experiments on a project basis
  • Manages time and balances work between bench and desk; completes tasks in timely manner
  • Manages a group of external scientists
  • Maintains accountability for ensuring own goals, those of any direct reports, project team goals, project and company objectives are achieved
  • Represents research/project team at high level meetings within the company
  • Maintains orderly and timely record of project plans and results in accordance with company policy and legal requirements
  • Makes broad scientific contributions that have a positive impact on the research direction of the company
  • Writes procedures/protocols and professional/technical reports and writes scientific articles, publications and patents
  • Represents the company effectively in scientific matters to external organizations
  • Maintains safe working environment for self and others

Qualifications

  • A PhD synthetic/medicinal chemist with 4-10 years of pharma/biotech-based drug discovery experience, with a track-record of leading/contributing to research projects towards IND-track nomination
  • A track record of creative contributions to drug design, especially structure-based design, optimizing pharmaceutical & DMPK properties and making critical scientific contributions at the project team level as a chemistry and/or project leader
  • A strong patent and publication record evidencing scientific curiosity and strong communication skills
  • Proficiency with database mining, graphing and interpretation
  • A successful candidate will have an enabling attitude, be a problem solver and have a desire to work in a collaborative manner across all the functional areas

Please send CV and cover letter to: careers@arvinas.com

Arvinas is proud to offer a competitive package of base and incentive compensation as well as a comprehensive benefits program designed to support the health, wellness and financial security of our employees and their families. Benefits include group medical, vision and dental coverage, group and supplemental life insurance, and much more. To learn more about Arvinas, please visit www.arvinas.com

Arvinas is an Equal Opportunity employer   

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Sr. Research Investigator/Associate Director, DEL Chemistry

Arvinas is a pharmaceutical company focused on developing new small molecules ‒ known as PROTACs (PROteolysis TArgeting Chimeras) ‒ aimed at degrading disease-causing cellular proteins via proteolysis. Based on innovative research conducted at Yale University by Dr. Craig Crews, Founder and Chief Scientific Advisor, the company is translating natural protein degradation approaches into novel drugs for the treatment of cancer and other diseases. The proprietary PROTAC-based drug paradigm induces protein degradation, rather than protein inhibition, using the ubiquitin proteasome system and offers the advantage of potentially targeting “undruggable” as well as “druggable” elements of the proteome. This greatly expands the ability to create drugs for many new, previously unapproachable targets. For more information, visit www.arvinas.com.

Position Summary

  • Design, synthesize, and analyze DNA Encoded Libraries (DELs)
  • Develop synthetic methods to enable novel DEL synthesis and/or to identify and implement innovative technologies
  • Analyze, interpret, and report experimental results at chemistry, program, and companywide meetings
  • Maintain detailed records of experiments in electronic lab notebooks in line with company policy
  • Contribute to conceptions, presentations, publications, and patents
  • Maintain a detailed knowledge of literature related to areas of research

Qualifications

  • Experience in Small Molecule Library Synthesis, Hit to Lead and/or Lead Optimization processes with strong interest in method development
  • Demonstrated ability to develop and follow multiple SAR treads for target/off-target potency and ADME optimization
  • Strong ability to design target molecules using both ligand and structure-based design principles
  • Experienced in using cheminformatics and other computational tools in drug design
  • Experience in purification and analytical methods (Preparative HPLC, SEC, LC/MS/MS, NMR)
  • Experience with operation, troubleshooting and maintenance of qTOF mass spectrometers and familiarity with automated liquid handlers is a plus
  • Ability to work effectively within a highly multidisciplinary team and experienced in collaborating across disciplines
  • Team spirit and excellent interpersonal skills
  • Ability to multitask while adhering to timelines
  • Self-motivated innovator with a focus on efficiency.
  • Excellent oral and written communication skills
  • Strong record of presentations, peer reviewed publications, and/or patents
  • Desire to lead initiatives in platform chemistry

Education

  • PhD in synthetic organic or medicinal chemistry with 5+ years medicinal chemistry experience in the pharmaceutical industry and 2+ years in DNA Encoded Library design and synthesis

 

Please send CV and cover letter to: careers@arvinas.com

 

Arvinas is proud to offer a competitive package of base and incentive compensation as well as a comprehensive benefits program designed to support the health, wellness and financial security of our employees and their families. Benefits include group medical, vision and dental coverage, group and supplemental life insurance, and much more. To learn more about Arvinas, please visit www.arvinas.com

Arvinas is an Equal Opportunity employer   

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CMC

Assoc. Director/Director, CMC External Manufacturing & Supply

Arvinas is a pharmaceutical company focused on developing new small molecules ‒ known as PROTACTM (PROteolysis TArgeting Chimera) protein degrader molecules ‒ aimed at degrading disease-causing cellular proteins via proteolysis. Based on innovative research conducted at Yale University by Dr. Craig Crews, Founder and Chief Scientific Advisor, the company is translating natural protein degradation approaches into novel drugs for the treatment of cancer and other diseases. The proprietary PROTAC-based drug paradigm induces protein degradation, rather than protein inhibition, using the ubiquitin proteasome system and offers the advantage of potentially targeting “undruggable” as well as “druggable” elements of the proteome. This greatly expands the ability to create drugs for many new, previously unapproachable targets. For more information, visit www.arvinas.com.

We are currently seeking an experienced and strategic individual to lead CMC manufacturing and supply at Arvinas. The Director will serve as a core member of a multidisciplinary project team and directly impact strategy, timing, and execution of both drug substance and drug product development and manufacturing.  A key responsibility of this role will be technical oversight of the associated CDMOs.  The qualified individual will have a track record of accomplishment in preparing RFPs, CDMO selection, contracting, and CDMO oversight.   This position reports to our VP of CMC and will work closely with the heads of Chemical Process R&D and Formulation R&D.  In addition, the Director will work closely with project teams to develop and execute a streamlined program to advance assets into clinic and then into commercialization. The incumbent will ensure all activities occur in compliance with the appropriate SOPs and regulations.

Primary Responsibilities

  • Design, lead, and implement a comprehensive API and DP supply chain strategy at Arvinas.
  • Working with the heads of Process and Formulation R&D, craft and distribute request-for-proposals to CDMOs to access intermediate, API, and DP supplies to enable the Arvinas pipeline.
  • Evaluate proposals and quotes matching the capabilities of the supplier with the project requirements in terms of quantity, quality, and timing of deliverables.
  • Working with the heads of Process and Formulation R&D select the best providers of service to meet project needs.
  • Working with internal and external legal resources craft master service agreements and contracts to reflect required deliverables.
  • As the primary contact with the contractors, manage day-today interactions to ensure that deliverables are completed as contracted.
  • Contribute to technical oversight of contracted suppliers in execution of API and DP-related deliverables.
  • Drive forecast planning and inventory management of all intermediates, APIs, and DPs to meet near-term and long-term goals. Incorporate risk-mitigation strategies.
  • Lead budget-planning for API and DP campaigns and track all spend relative to budget.
  • Communicate production schedules to Project Management and the project team as part of project Integrated Development Plans for Arvinas assets.
  • Manage the CMC Supply Chain interfaces with Clinical Supply, Clinical Operations, Quality Assurance, and Regulatory Compliance.
  • Participate in strategy discussions to ensure that decisions align with agreed upon business direction and processes.
  • Lead the collection of relevant data and reports from suppliers to enable drafting of INDs, NDAs, and associated amendments.

Qualifications

  • A Ph.D in Chemistry, Pharmaceutics, or Chemical Engineering or related technical field and 10+ years relevant experience in CMC operational roles, preferably in a bio-tech environment.
  • A successful history of hands-on chemical, and/or formulation development and scale-up.
  • A successful track record in the RFP/contracting process along with detailed technical oversight of third-party contractors.
  • Experience with management of all stages API and DP development and manufacturing.
  • Comprehensive working knowledge of Good Manufacturing Practices (cGMPs) and regulatory guidance documents as they relate to manufacture and quality testing of pharmaceutical products.
  • Demonstrated experience in inventory management and forecasting.
  • Ability to effectively prioritize and deliver on tight timelines
  • Outstanding problem-solving abilities
  • Detail-oriented, with good organizational and project management skills
  • Good oral and written communications skills
  • Proficient with MS Word, PowerPoint, Excel
  • Strong leadership, project planning, negotiation and presentation skills
  • Significant experience in communicating/presenting complex information to senior management and regulatory agencies.
  • Ability to multi-task and manage several projects in parallel, paying attention to detail.
  • Ability to forge cross-functional working relationships with internal and external project partners
  • Ability to be proactive in identifying issues and hurdles that may hinder the effective progression of an asset and resolve the issues in a timely and creative fashion

Please send CV and cover letter to: careers@arvinas.com

Arvinas is proud to offer a competitive package of base and incentive compensation as well as a comprehensive benefits program designed to support the health, wellness and financial security of our employees and their families. Benefits include group medical, vision and dental coverage, group and supplemental life insurance, and much more. To learn more about Arvinas, please visit www.arvinas.com

Arvinas is an Equal Opportunity employer   

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G & A

Associate Director, Corporate and Commercial Development

 

Arvinas is a biopharmaceutical company creating new small molecules ‒ known as PROTACs (PROteolysis TArgeting Chimeras) ‒ that degrade disease-causing cellular proteins via proteolysis. Based on innovative research conducted at Yale University by Dr. Craig Crews, Founder and Chief Scientific Advisor, the company is translating natural protein degradation approaches into novel drugs for the treatment of cancer, neurological disorders, and other diseases. The proprietary PROTAC-based drug paradigm induces protein degradation, rather than protein inhibition, using the ubiquitin proteasome system and offers the advantage of potentially targeting “undruggable” as well as “druggable” elements of the proteome. This greatly expands the ability to create drugs for many new, previously unapproachable targets.

Arvinas is at exciting stage in its growth as a company.  The company expects its first two drug candidates, ARV-110 and ARV-471, to enter the clinic in 2019 for patients with prostate cancer and breast cancer, respectively.  Also in 2019, Arvinas expects to present compelling new data on its neurodegeneration program (tau).  Arvinas is growing rapidly, having roughly doubled in size in 2018 while also completing its initial public offering (IPO; NASDAQ:ARVN).  For more information, visit www.arvinas.com.

Position Summary

At Arvinas, Corporate Development includes responsibilities in Corporate Strategy, Commercial Development, Business Development, Investor Relations, and Communications.  The Associate Director, Corporate and Commercial Development will report to, work closely with, and be a key strategic partner to the Vice President, Corporate Development.  The ideal candidate will be excited to roll up their sleeves across multiple disciplines in a fast-paced, entreprenurial environment.

Given the breadth of responsiblities, there is flexibility with regards to both candidate experience and to how the various responsiblities below are prioritized.

Principal Responsibilities

This will be a high-profile role where the candidate will gain firsthand strategic and operating experience while helping to build a premier biopharmaceutical company. The high energy individual will “wear many hats” and have the capacity to drive numerous complex projects forward simultaneously. This position will require both strategic and operational excellence while working closely with senior management and business partners.

Corporate Strategy

  • Develop and maintain strategic frameworks to make decisions regarding the prioritization of new targets, therapeutic areas, and disease states
  • Provide input and support to new target prioritization
  • Understand disease biology, mechanism of potential intervention, current treatment paradigms and competitive landscape to inform decisions regarding potential clinical programs
  • Support the strategic planning process, as well as strategic input to annual budget planning
  • Build and own long-term corporate financial models for Arvinas, including scenario analyses
  • With stakeholders across the company, reinforce and communicate Arvinas’ mission
  • Ensure Arvinas’ corporate strategy is reflected consistently across internal materials, investor presentations, and external communications
  • Support the development of presentations to the senior team and/or board of directors
  • Identify critical risks to Arvinas’ strategy and prioritize potential mitigations
  • Work directly with the executive team to prioritize and lead strategic initiatives

Commercial Development

  • Lead commercial analyses/assessments for portfolio prioritization and decisions across therapeutic areas and indications
  • Develop and communicate strong understanding of treatment protocols, unmet needs, potential patient segments, and competitive pipeline in order to identify targeted product concepts and necessary product profiles
  • Create and maintain target product profiles (TPP) for potential and pipeline assets
  • Provide strategic commercial input to pipeline programs in early and mid-stage development
  • Develop business cases for prioritized targets
  • Conduct diligence on competitors/precedents to inform business cases
  • Provide commercial input to clinical trial design, regulatory approaches, and other aspects of development
  • Provide commercial forecasting and analytical support for pipeline programs in the long-range plan
  • Provide commercial input to business development opportunities
  • Develop and maintain competitive intelligence views for pipeline programs

Business Development

  • Conduct competitive and business/financial analysis to support the transaction process, including benchmarking of analogous BD deals
  • Contribute to BD strategy by analyzing scientific and industry trends and competitive environment
  • Create and maintain valuation models of potential transactions, executing scenario analyses, and evaluating alternative deal constructs
  • Support the development of BD materials and presentations

Education & Qualifications

  • BA/BS degree required; advanced degree preferred
  • 4+ years total relevant work experience (pharmaceuticals or biotech) required
  • Within biopharmaceuticals, experience in business development or commercial development (or new product planning) preferred
  • Outside biopharmaceuticals, experience in management consulting, banking, private equity, or venture capital preferred
  • Oncology experience is a plus
  • Previous hybrid experience in financial and scientific/commercial analysis strongly preferred

Competencies

  • High self-motivation and aptitude for working in a dynamic, collaborative, fast paced, and deadline-driven environment
  • Ability to build relationships at all levels and across diverse areas of the company, including Research and Development, Legal, CMC, and Finance
  • Adept at facilitating productive discussion and debate by listening effectively and managing stakeholders
  • Passion for helping patients through innovative science
  • Independent, persistent problem solving and the ability to work successfully with ambiguity
  • Strong analytical and problem-solving skills; ability to combine attention to detail with big picture perspective
  • Desire and ability to manage multiple complex projects simultaneously
  • Good knowledge of drug discovery, development, and commercialization processes
  • Excellent written, verbal, computer and social media knowledge and skills
  • Excellent communication, organizational, and planning skills
  • Strong Microsoft Office (Excel, Outlook, Word, PowerPoint) skills
  • Public biotech company experience preferred
  • Knowledge in oncology/immuno-oncology therapeutic area preferred

Please send CV and cover letter to: careers@arvinas.com

Arvinas is proud to offer a competitive package of base and incentive compensation as well as a comprehensive benefits program designed to support the health, wellness and financial security of our employees and their families. Benefits include group medical, vision and dental coverage, group and supplemental life insurance, and much more. To learn more about Arvinas, please visit www.arvinas.com

Arvinas is an Equal Opportunity employer   

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IT

Laboratory Information Management System Manager

Arvinas is a pharmaceutical company focused on developing new small molecules ‒ known as PROTACs (PROteolysis TArgeting Chimeras) ‒ aimed at degrading disease-causing cellular proteins via proteolysis. Based on innovative research conducted at Yale University by Dr. Craig Crews, Founder and Chief Scientific Advisor, the company is translating natural protein degradation approaches into novel drugs for the treatment of cancer and other diseases. The proprietary PROTAC-based drug paradigm induces protein degradation, rather than protein inhibition, using the ubiquitin proteasome system and offers the advantage of potentially targeting “undruggable” as well as “druggable” elements of the proteome. This greatly expands the ability to create drugs for many new, previously unapproachable targets. For more information, visit www.arvinas.com.

Arvinas is seeking a Laboratory Information Management System (LIMS) Manager to oversee and implement our LIMS system.  This individual will work closely with Arvinas’ scientists to gain a deep understanding of the scientific goals of each approach in order to develop custom workflows that ensure efficient data management and traceability.  The position requires technical knowledge in lab data management and processing in addition to interpersonal effectiveness required to drive a smooth implementation.  This position will work closely with other core R&D functions at Arvinas, including laboratory automation, IT, bioinformatics, and cheminformatics to provide researchers with a world class R&D platform.

Primary Responsibilities

  • Develop and support Core LIMS / SDMS / ELN in collaboration with vendor
  • Participate in requirements-gathering and solution review sessions and assist in writing user requirements documentation, including Entity Relationship Diagrams (ERDs).  Unify requirements across labs.
  • Manage migration of legacy LIMS and ELN infrastructure to Core LIMS
  • Effectively implement Core LIMS, providing ongoing training
  • Serve as Tier 1 support to laboratory staff:  triage questions from internal team, facilitate resolution, reproduce identified issues and liaise with Core Informatics on items that cannot be resolved through additional training or configuration
  • Develop User Acceptance Test (UAT) scripts for implemented configurations
  • Develop internal SOPs for platform use and supporting processes
  • Collaborate with R&D scientists and other core functions to outline current research needs and workflows
  • Build a LIMS development and implementation roadmap, providing well-defined timelines and deliverables
  • Generate proper documentation and follow change control best practices
  • Work within broader software development efforts, utilizing repositories, participating in code reviews, and using best practices for testing and deployment of software
  • Ensure cohesive implementation and data integrity across laboratory automation platforms and databases

Qualifications

  • Bachelor’s degree in IT, computer programming, software engineering, or related program
  • 3+ years’ experience in life sciences IT support and/or LIMS development
  • Strong interpersonal effectiveness, able to build trust and drive adoption of new software platforms
  • Experience with relational databases, including working knowledge of PostgreSQL, Oracle, and SQL Server
  • Experience in ETL, data mapping, SQL scripting, and REST API
  • Experience with relevant programming languages, such as .NET, C#, Java, JavaScript, R, and/or Python
  • Experience with Core LIMS, Certara D360, and McNeil Co ACAS is highly desirable
  • Experience with data pipelining tools such as KNIME and/or Pipeline Pilot desirable
  • Experience with data visualization tools/languages (e.g., R, Spotfire, Tableau)

Please send CV and cover letter to: careers@arvinas.com

Arvinas is proud to offer a competitive package of base and incentive compensation as well as a comprehensive benefits program designed to support the health, wellness and financial security of our employees and their families. Benefits include group medical, vision and dental coverage, group and supplemental life insurance, and much more. To learn more about Arvinas, please visit www.arvinas.com

Arvinas is an Equal Opportunity employer   

Continue reading →