Associate Director, Director, Senior Director of Platform Biology

PhD-level position dedicated to conducting experiments to further understand the underlying principles of PROTAC-mediated protein degradation.

 

Education and Training

  • Ph.D, with 15+ years of pharma- or biotech experience in cellular and molecular biology, pharmacology, biochemistry, biophysics or enzymology. Focus on cancer cell biology and drug discovery strongly preferred.

Requirements

  • Innovative, creative, inquisitive, motivated researcher with strong problem-solving skills and demonstrated ability to advance new scientific understanding
  • Experience in the ubiquitin-proteasome system, or targeted protein degradation, preferred
  • Strong expertise in cancer cell biology, drug discovery approaches and biochemical and biophysical techniques
  • Strength in running and evaluating experiments to measure target engagement, protein degradation, pathway modulation and therapeutic sensitivity in response to compounds
  • Experience in developing assays to profile compounds using mechanistic and functional readouts
  • Demonstrated success in working on a cross-disciplinary, drug discovery project team; integrating and evaluating the work of multiple drug discovery groups / functions
  • Expertise in developing compound profiling assays to support chemistry efforts in developing structure-activity relationships
  • Excellent communication and interpersonal skills
  • Supervisory experience

Other Preferred Skills and Knowledge

  • Manages times and balances work between bench and desk
  • Maintains accountability for ensuring own goals, those of any direct reports and company objectives are achieved
  • Maintains a safe working environment for self and others
  • Represents the company effectively to external organizations and to the Board of Directors and other company senior management, as needed/requested
  • Writes procedures/protocols and professional/technical reports and writes scientific articles, publications and patents

Location

New Haven, CT

Please send CV and cover letter to:Ā careers@arvinas.com.