Arvinas is a pharmaceutical company focused on developing new small molecules ‒ known as PROTACs (PROteolysis TArgeting Chimeras) ‒ aimed at degrading disease-causing cellular proteins via proteolysis. Based on innovative research conducted at Yale University by Dr. Craig Crews, Founder and Chief Scientific Advisor, the company is translating natural protein degradation approaches into novel drugs for the treatment of cancer and other diseases. The proprietary PROTAC-based drug paradigm induces protein degradation, rather than protein inhibition, using the ubiquitin proteasome system and offers the advantage of potentially targeting “undruggable” as well as “druggable” elements of the proteome. This greatly expands the ability to create drugs for many new, previously unapproachable targets. For more information, visit www.arvinas.com.
An ideal candidate would have a well-trained background in molecular modeling or computational chemistry, having the flexibility to be integrated into the current group as well as work collaboratively with chemists and biologists and having the desire to learn and solve challenging problems. Extensive experience in molecular dynamics simulation, free energy prediction or protein-protein docking is highly sought. This position reports to the Director of Computational Chemistry and will be located at our headquarters in New Haven, CT.
Key responsibilities of this role include, but are not limited to:
Please send CV and cover letter to: firstname.lastname@example.org
Arvinas is proud to offer a competitive package of base and incentive compensation as well as a comprehensive benefits program designed to support the health, wellness and financial security of our employees and their families. Benefits include group medical, vision and dental coverage, group and supplemental life insurance, and much more. To learn more about Arvinas, please visit www.arvinas.com
Arvinas is an Equal Opportunity employer